Tuesday, October 18, 2016

Vpriv


Pronunciation: VEL-a-GLOO-ser-ase AL-fa
Generic Name: Velaglucerase alfa
Brand Name: Vpriv


Vpriv is used for:

Treating type I Gaucher disease.


Vpriv is an enzyme. It breaks down a substance (glucocerebroside) that builds up in the body in patients with Gaucher disease. This helps to decrease the harmful effects of the disease.


Do NOT use Vpriv if:


  • you are allergic to any ingredient in Vpriv, unless your doctor tells you otherwise

Contact your doctor or health care provider right away if any of these apply to you.



Before using Vpriv:


Some medical conditions may interact with Vpriv. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Vpriv. However, no specific interactions with Vpriv are known at this time.


Ask your health care provider if Vpriv may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Vpriv:


Use Vpriv as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Vpriv is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Vpriv at home, a health care provider will teach you how to use it. Be sure you understand how to use Vpriv. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.

  • Gently swirl Vpriv when mixing. Do not shake.

  • If Vpriv contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it.

  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.

  • If you miss a dose of Vpriv, contact your doctor for advice on when to schedule the next dose.

Ask your health care provider any questions you may have about how to use Vpriv.



Important safety information:


  • Vpriv may cause dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Vpriv with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Infusion-related reactions may occur with Vpriv. These reactions have usually been mild, and have occurred mostly within the first 6 months of treatment with Vpriv. Tell your doctor if you experience headache, dizziness, nausea, tiredness, weakness, or fever when you receive Vpriv.

  • Caution is advised when using Vpriv in CHILDREN; they may be more sensitive to it effects, especially the risk of upper respiratory tract infection, fever, rash, and decreased blood clotting.

  • Vpriv should be used with extreme caution in CHILDREN younger than 4 years old; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you plan on becoming pregnant, contact your doctor. You will need to discuss the benefits and risks of using Vpriv during pregnancy. It is not known if Vpriv is found in breast milk. If you are or will be breast-feeding while you are using Vpriv, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Vpriv:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Back or joint pain; dizziness; fever; headache; nausea; stomach pain; tiredness; upper respiratory tract infection; weakness.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fast heartbeat; severe or persistent dizziness or headache; unusual bruising or bleeding.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Vpriv side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.


Proper storage of Vpriv:

Vpriv is usually handled and stored by a health care provider. If you are using Vpriv at home, store Vpriv as directed by your pharmacist or health care provider. Keep Vpriv out of the reach of children and away from pets.


General information:


  • If you have any questions about Vpriv, please talk with your doctor, pharmacist, or other health care provider.

  • Vpriv is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Vpriv. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Vpriv resources


  • Vpriv Side Effects (in more detail)
  • Vpriv Use in Pregnancy & Breastfeeding
  • Vpriv Support Group
  • 0 Reviews for Vpriv - Add your own review/rating


  • Vpriv Prescribing Information (FDA)

  • Velaglucerase alfa Professional Patient Advice (Wolters Kluwer)

  • VPRIV Advanced Consumer (Micromedex) - Includes Dosage Information

  • VPRIV Consumer Overview



Compare Vpriv with other medications


  • Gaucher Disease

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